Quorum Regulated Resistance of Vibrio cholerae against Environmental Bacteriophages

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Quorum Regulated Resistance of Vibrio cholerae against Environmental Bacteriophages

Predation by bacteriophages can significantly influence the population structure of bacterial communities. Vibrio cholerae the causative agent of cholera epidemics interacts with numerous phages in the aquatic ecosystem, and in the intestine of cholera patients. Seasonal epidemics of cholera reportedly collapse due to predation of the pathogen by phages. However, it is not clear how sufficient ...

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The factors that enhance the waterborne spread of bacterial epidemics and sustain the pathogens in nature are unclear. The epidemic diarrheal disease cholera caused by Vibrio cholerae spreads through water contaminated with the pathogen. However, the bacteria exist in water mostly as clumps of cells, which resist cultivation by standard techniques but revive into fully virulent form in the inte...

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Cholera continues to be endemic in a large geographical tract covering a number of states in the eastern, western and southern parts of India. Even though V. cholerae non-01 has been reported from some parts of Delhi(l), V. cholerae-01 biotype Eltor continues to be the main etiological agent identified from Delhi(2). Rapid replacement of fluid and electrolyte using oral rehydration therapy or i...

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Cholera epidemics have long been known to spread through water contaminated with human fecal material containing the toxigenic bacterium Vibrio cholerae. However, detection of V. cholerae in water is complicated by the existence of a dormant state in which the organism remains viable, but resists cultivation on routine bacteriological media. Growth in the mammalian intestine has been reported t...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2016

ISSN: 2045-2322

DOI: 10.1038/srep37956